Congrats on the new2u compressor. I just bought one myself, there quite useful.
Question: Is it a belt drive/oiled compressor, or oil less. Reason I say that is at 33g oiled it's not going to move very often. You might been a maintenance window for oil changes etc. Tank drain.
What I would try and do, Make it quieter yet useable. Is there a way to build this box into a bench or something. Have it sit under a table.
1. I would work a ventilation system into the design, your going to need a hole of some kind. I would say a good sized with a mesh sandwiched with breathable material to cover it. Are you talking powered? As in fan driven, or not.
2. I'd see how much heat it puts out. Yes I'd be concerned about it and take it into consideration. You don't want it over heating or going into thermal shutdown. Maybe take measurements inside the box to see what it running at.
I would also try include.
Remote tank drain
Remote air regulator/guages
Rubber Pads to reduce vibration.
Take pictures of the build. I'd love to see how it turns out. Goodluck