I was there for the first time in August. I stayed right downtown and did some touristy stuff. Gastown and Granville Island. On opposite ends of downtown/Granville St. Both have intersting shops and restaurants. Stanley Park is beautiful and can be time consuming. Davies St. has a bunch of interesting stuff as well. It seemed to be the gay district so you may get more than you bargained for. There's also the Capilano Suspension Bridge and Grouse Mountain in North Vancouver but both would be time consuming. That's basically what I did but locals on here may want to give you some better info.